Bisfenol A

Bisfenol A - un perturbador endocrino

El bisfenol A puedo encontrarse en envases de alimentos y bebidas

¿Qué es el bisfenol A?
El bisfenol A, llamado también BPA, es una sustancia química empleada desde el decenio de 1960 para fabricar plásticos duros de peso leve y resinas epoxídicas. En su forma pura, es una sustancia sólida de color blanco, con olor medicinal. En los Estados Unidos se producen más de mil millones de libras de BPA al año.

Los productos de plástico fabricados con BPA suelen ser transparentes y duros y se llaman plásticos policarbonados. Entre ellos cabe citar envases de alimentos y bebidas, botellas de agua, biberones para lactantes y bebés, tazas de alimentación de bebés, tazas reutilizables, discos compactos, piezas de repuesto para automóviles, equipo de seguridad resistente a los choques, cubiertos de plástico, lentes para anteojos, juguetes y dispositivos médicos. Las resinas epoxídicas fabricadas con BPA se emplean como lacas para revestimiento de productos de metal como latas metálicas de alimentos y barriles de vino con superficie interior revestida, tapas de botellas, materiales para pisos, pinturas y tubos del sistema de acueducto. Algunos materiales ignífugos y selladores y compuestos dentales también pueden contener BPA. Esta sustancia también se usa en el reciclaje del papel térmico, como recibos, etiquetas autoadhesivas y papel de fax, y en la fabricación de plásticos de cloruro de polivinilo.

Los productos de plástico fabricados con BPA llevarán un símbolo de reciclaje con el número 7 o las letras “PC” cerca del símbolo de reciclaje. El BPA no es uno de los ftalatos encontrados en los plásticos blandos.

http://toxtown.nlm.nih.gov/espanol/chemicals.php?id=70

Bisphenol A in Children's Dentistry

"Dental sealants and composite filling materials containing Bisphenol A (BPA) derivatives are increasingly used in childhood dentistry. Evidence is accumulating that BPA and some BPA derivative can pose health risks attributable to their endocrine-disrupting properties."

Excerpt from article published in Paediatrics 2010.

Comment from Dr. Louis Niestegge,, Bonn
"It must be mentioned that bisphenol A is also present in almost all dental plastics, which means that there is an immunotoxic problem in addition to the toxicological problem. The estrogen effect of BPA released from dental fillings is described in the literature."
Information from the GZM (Society for Holistic Dentistry).

Analysis

Blood

Needed Material: 3-5ml Whole Blood

Urine

Needed Material: 5-7ml Urine

Saliva

Needed Material: 3ml Saliva

Water

Needed Material: 5-7ml Water

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More Information about BPA

Toxicological and Health Aspects of Bisphenol A

Report of Joint Food and Agriculture Organization of the United Nations (FAO) and World Health Organization (WHO) - Expert Meeting:

Análisis

Sangre

Material necesario: 3-5ml de sangre

Orina

Material necesario: 5-7ml de orina

Saliva

Material necesario: 3ml de saliva

Aqua

Material necesario: 5-7ml de agua

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Bisphenol A Impairs Mitochondrial Function in the Liver at Doses below the No Observed Adverse Effect Level

Min Kyong Moon,^1,^*Min Joo Kim,^1,^2,^*In Kyung Jung,^1,²Young Do Koo,¹Hwa Young Ann,^1,²Kwan Jae Lee,²Soon Hee Kim,¹Yeo Cho Yoon,²Bong-Jun Cho,²Kyong Soo Park,¹Hak C. Jang,^1,² and Young Joo Park^1,2

Bisphenol A (BPA) has been reported to possess hepatic toxicity. We investigated the hypothesis that BPA, below the no observed adverse effect level (NOAEL), can induce hepatic damage and mitochondrial dysfunction by increasing oxidative stress in the liver. Two doses of BPA, 0.05 and 1.2 mg/kg body weight/day, were administered intraperitoneally for 5 days to mice. Both treatments impaired the structure of the hepatic mitochondria, although oxygen consumption rate and expression of the respiratory complex decreased only at the higher dose. The hepatic levels of malondialdehyde (MDA), a naturally occurring product of lipid peroxidation, increased, while the expression of glutathione peroxidase 3 (GPx3) decreased, after BPA treatment. The expression levels of proinflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) also increased. In HepG2 cells, 10 or 100 nM of BPA also decreased the oxygen consumption rate, ATP production, and the mitochondrial membrane potential. In conclusion, doses of BPA below the NOAEL induce mitochondrial dysfunction in the liver, and this is associated with an increase in oxidative stress and inflammation.

BPA Exposure Linked To Asthma In Kids

The list of adverse health effects from BPA exposure continues to grow.

Bisphenol A, or BPA, is commonly used to line food and beverage cans, and helps to keep plastics flexible, but studies suggest the compound can leach into the foods we eat. High levels of BPA in the urine have been tied to behavior problems, obesity, hormone abnormalities and even kidney and heart problems. Now, new research from scientists at the Columbia Center of Children’s Environmental Health is linking the compound to an increased risk for asthma.